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Diagnostics · Rhythm

Cadence

Digital phenotyping, from the wrist.

A behavioural rhythm monitoring platform that turns continuous wearable data — sleep, activity, heart-rate variability — into a per-patient rhythm signature. Built with an FDA-grade audit trail for use inside clinical trials.

CadenceDiagnostics · Rhythm

Wearables produce oceans of data. Cadence produces signal.

A patient connects Apple Health, Google Fit, an Oura ring, or a Fitbit, and the raw data starts flowing in: step counts, sleep stages, heart rate, HRV. Most platforms stop there and hand you a dashboard. Cadence goes further, cleaning and aligning the streams into one time-series per patient.

On top of that, Cadence computes a rhythm signature — a small set of reproducible metrics describing when a patient is active, when they rest, and how consistent those cycles are over weeks. Clinical trials can use this signature as an endpoint or dose-response signal. Every calculation is logged for audit, with regulator-grade storage on the near-term roadmap.

Features

Everything a trial needs from a wearable — and nothing it doesn't.

01

Continuous ingestion

Apple HealthKit, Google Fit, Oura, and Fitbit streams — normalised into a single canonical schema.

02

Rhythm signatures

Reproducible per-patient metrics — activity amplitude, phase, fragmentation — computed from clean, aligned streams.

03

Application-level audit log

Every ingestion, transformation, and derivation is logged. Database-level immutability (21 CFR Part 11 / pgaudit) is on the roadmap, not yet live.

04

Trial-ready

Cohort management, endpoint dashboards, and structured exports built for CROs and trial sponsors.

Open Cadence

Cadence is available as an API to research partners now. Consumer-facing apps are in build.

Cadence's API is live for research partners today; end-user apps are in build.

Coming soon
Side A

For patients

A companion app for enrolled participants — pairing wearables, viewing personal rhythm trends, and completing brief in-app check-ins. In build.

Coming soon
Side B

For principal investigators

Study dashboards with cohort views, endpoint tracking, and audit-ready exports. In build; API access available to research partners today.

Cadence is one of the research tools built inside the Synapse Spark Foundation. Everything we make is part of the same mission — understanding neurodivergent minds and supporting the researchers advancing the science.

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