We study how minds work, build solutions for clinicians and families, and fund the scientists doing the work.
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One account, every Synapse Spark tool. Choose your role below and you'll be signed up in under a minute. Patients get access right away. Clinicians and researchers get an account immediately, and a human at the foundation reviews your tool access before you can open the clinical or research surfaces.
Track your own or your child's care across every Synapse tool your clinician has enrolled you in. See your recommendations, your check-ins, and your care team in one place.
Give your patients tools that match how their minds actually work. Titration, screening, adherence, decision support — clinical-grade and built with clinicians who see this every day.
Access de-identified registries, run cohort analyses, or apply to one of our four open research programmes. Open data, open methods, no restrictive IP.
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What we believe
You may think, focus, feel, and remember differently than what's considered typical. That's not something to fix — it's part of who you are. Our science, our solutions, and our care start from you.
Your traits are variation, not something to fix. We study how your mind actually works — attention, memory, sleep, mood. Your care should fit who you are, not who you're expected to be.
What we build starts with what's missing. We hear it from families, from clinicians without the right tools, and from neurodivergent adults living this every day. Every solution begins as a real question someone asked us.
Our findings, data, and clinical tools belong to the communities they came from — including yours. We publish openly and welcome scrutiny. Nothing is locked away.
The goal isn't to make your mind fit the world. It's to make the science and the solutions finally fit your mind.— our founding principle
What we build
Each solution is its own research programme — built with clinicians, tested with families, and open to academic collaboration. Together they cover everything from first screening to precision therapy to frontier discovery.
Objective attention assessment
Browser-based Continuous Performance Test. Calibration-gated, clinical-grade precision, no download required. Runs in a school nurse's office or a family kitchen.
Open FocalBehavioural rhythm monitoring
Digital phenotyping from wearable sleep and activity streams. Computes an ADHD drug-response signature with an FDA-grade audit trail.
Open CadencePediatric dysregulation infrastructure
Research infrastructure for pediatric dysregulation studies. Ingests wearable and app data, computes dysregulation signatures, and gives researchers the query tools they've been building by hand in spreadsheets.
Open TidewaterTrigeminal stimulation companion
Adherence tracking, symptom diary, and clinician dashboard for external trigeminal nerve stimulation therapy in adult ADHD.
Open VesperAdaptive coaching
Biosensing just-in-time adaptive interventions. Rejection-sensitivity safeguards, per-person tuning, and consent-gated wellbeing tracking.
Open LullMultimodal treatment matching
Combines symptoms, comorbidities, pharmacogenomics, and lifestyle into ranked treatment considerations. Clinical decision support, never autopilot.
Open PrismTitration engine
Embeddable pharmacokinetic dosing for stimulants and non-stimulants. Eight drugs, six genes, forty CPIC reference cards, SMART-on-FHIR ready.
Open LadderReal-world evidence
OMOP-aligned ADHD registry. HIPAA Safe Harbor de-identification, FHIR / HL7v2 / CSV ingestion, k-anonymity-enforced cohorts for researchers.
Open AlluvionClinical trial eligibility
Psychiatry-native eligibility rail for CNS and ADHD trials. Parses psychiatric EHR data to flag candidates for human review — never auto-enrolls.
Open ArborDLMO-guided chronotherapy & stepped care
DLMO-guided light scheduling, melatonin timing, and wearable sleep tracking for ADHD. Async coaching and clinical escalation to sleep-psychiatry when self-management isn't enough.
Includes a clinical telehealth arm →
Open Aubade4-subtype ADHD classifier
Deterministic four-subtype classifier using eye-tracking and cognitive features. Confidence-gated with an indeterminate path — no false certainty.
Open FacetCompound repurposing
Non-stimulant repurposing platform. Deterministic target scoring against eight ADHD-relevant classes, knowledge graph, licensing pipeline for researchers.
Open ReposeHow we support research
We run four open research programmes, each supporting a different stage of the work — from an early idea that needs seed funding to a team ready to bring a finding into clinical use. Applications are open worldwide.
Seed support for early-stage neurodiversity research. Open to researchers worldwide, at any career stage.
Bridging lab findings to clinical application. We encourage technology-enabled, multi-institution work.
Ring-fenced support for the most common — and least funded — comorbidity in child psychiatry.
Direct support for advocacy, education, and community organisations led by neurodivergent people themselves.
Applications are reviewed on a rolling basis. We prefer scientific rigour and lived experience in equal measure.
Apply for a programmeWho we work with
We work in the open with universities, clinical teams, advocacy organisations, and — most important — neurodivergent people themselves. The best research happens where academic rigour meets lived experience.
Partner institutions test our screening and assessment solutions through IRB-approved studies. We publish every result — positive, negative, or unclear — in full.
Accredited academic researchers can access our de-identified ADHD registry under standard data-use agreements — a faster, cheaper way to get a real-world signal.
We are building the first dedicated research programme for the ADHD+ODD overlap, with pediatric psychiatry departments and family advocacy groups.
Competitive sponsored research at partner universities. Neurodevelopmental focus, open-access publication requirement, no restrictive IP.
Get involved
Five doorways into our work. Pick the one that fits — the door isn't the point, the work behind it is.
Apply for programme funding, request data-commons access, or propose a collaboration on a specific solution.
Apply or collaborate →Access clinical solutions, contribute to validation studies, or join our clinical advisory network.
See our solutions →Understand your own or your child's neurodiversity through a strengths-based lens. Community resources and support.
Get in touch →Universities, pharmaceutical sponsors, and technology partners: co-develop, license, or fund a specific programme.
Partner with us →Fund a specific instrument, join the Founding Donor Circle, or support general operations. See exactly what your gift funds, with progress reports.
Give to the Foundation →Looking for a tool account instead of a collaboration? Jump to sign up →
We read every message and reply to almost all of them. The more you tell us about your work or what you need, the more useful our reply will be.
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