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Precision Medicine · Matching

Prism

ADHD treatment matching, multimodal.

Combines diagnostic subtype, digital-phenotype signals, cohort priors, and pharmacogenomics into ranked treatment considerations. Clinical decision support — never autopilot.

PrismPrecision · Matching

A ranked list is not a diagnosis. It's a starting point.

ADHD treatment is high-variability medicine. Two patients with the same symptom profile can respond to very different treatments — one does well on a long-acting stimulant, the other can't tolerate it and does better on a non-stimulant with sleep support. Clinicians have always known this; the tools to structure that reasoning haven't kept up.

Prism combines four kinds of input into a ranked set of treatment options:

  • Diagnostic subtype
  • Digital-phenotype signal from the Foundation's other tools
  • Cohort-level priors
  • Pharmacogenomic markers, where available

Every ranking is explainable and points back to its inputs. The clinician still makes the call — Prism just makes the case load lighter. It's currently in a pre-calibration stage: rankings are directional, not yet calibrated against a real treated cohort.

Features

Decision support — with the emphasis on support.

01

Multimodal inputs

Diagnostic subtype, digital-phenotype signal, cohort priors, and pharmacogenomics — combined into one coherent view of the patient.

02

Ranked considerations

A ranked list — never a single recommendation. The clinician sees the top options and the reasons each one is there.

03

Guideline-aware

Priors grounded in AACAP ADHD clinical guidance and published pharmacogenomic literature.

04

Explainable

Every ranking shows its inputs. No black box — the reasoning is legible enough to argue with.

Open Prism

One tool — two audiences.

Clinicians use Prism at the point of care. Administrators keep the deployment configured, updated, and secure.

Side A

For clinicians

Structured patient intake and ranked treatment considerations. Every ranking is explainable at the point of use.

Open the clinician tool
Side B

For administrators

Clinic configuration, audit log, and user management. Keep the deployment aligned to institutional policy.

Open the admin console

Not started

Where the evidence stands: the study that would validate the central claim has not begun — the evidence page says what it is and what result would kill this.

Read the evidence ladder →

Prism is one of the solutions built inside the Synapse Spark Foundation. Everything we make is part of the same mission — embracing neurodivergent minds and supporting the researchers advancing the science.

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